​2024

Extracellular vesicle bioactivity and potential clinical utility is determined by mesenchymal stromal cell clonal subtype
bioRxiv
​Ioannou S, Kay AG, Stone AP, Rand E, Elberfeld S, Bolton W, Larson T, Crossland RE, Kehoe O, Mentlak DA, Wang XN, MacDonald C, Genever PG.

High resolution live cell imaging to define ultrastructural and dynamic features of the halotolerant yeast Debaryomyces hansenii
bioRxiv
Xelhuantzi MSC, Ghete D, Milburn A, Ioannou S, Mudd P, Calder G, Ramos J, O’Toole PJ, Genever PG, MacDonald C.

iPAR: a new reporter for eukaryotic cytoplasmic protein aggregation
bioRxiv
Lecinski S, MacDonald C, Leake MC.


2022

The phosphatase Glc7 controls eisosomal response to starvation via posttranslational modification of Pil1 
bioRxiv
Paine K, Evans G, Laidlaw KM, MacDonald C.

Correlating viscosity and molecular crowding with fluorescent nanobeads and molecular probes: in vitro and in vivo
bioRxiv
Lecinski S, Shepherd J, Bunting K, Dresser L, Quinn S, MacDonald C, Leake MC.


2021

The Rpd3-complex regulates expression of multiple cell surface recycling factors in yeast
bioRxiv
Amoiradaki K, Bunting KR, Paine KM, Ayre JE, Hogg K, Laidlaw KM, MacDonald C.

Investigating molecular crowding during cell division in budding yeast with FRET
bioRxiv
Lecinski S*, Shepherd JW*, Frame L, Hayton I, MacDonald C, Leake MC.

Recycling of nutrient transporters from yeast endosomes is regulated by ubiquitinated Ist1
bioRxiv
Laidlaw K, Calder G, MacDonald C. 

Fur4 mediated uracil-scavenging to screen for surface protein regulators
bioRxiv
Paine K, Ecclestone G, MacDonald C. 

Endosomal recycling to the surface mediated by Gpa1 and PI3-Kinase is inhibited by glucose starvation
bioRxiv
Laidlaw K*, Paine K*, Bisinski D, Calder G, MacDonald C. 


2020

Molecular crowding in single eukaryotic cells: using cell environment biosensing and single-molecule optical microscopy to probe dependence on extracellular ionic strength, local glucose conditions, and sensor copy number
bioRxiv
Shepherd JW, Lecinski S, Wragg J, Shashkova S, MacDonald C, Leake MC.

A glucose starvation response governs endocytic trafficking and eisosomal retention of surface cargoes
bioRxiv
Laidlaw KM, Bisinski DD, Shashkova S, Paine K, Veillon MA, Leake MC & MacDonald C.


2017

COPI mediates recycling of an exocytic SNARE from endosomes by recognition of a ubiquitin sorting signal
bioRxiv
Xu P, Hankins H, MacDonald C, Erlinger S, Frazier M, Diab N, Piper RC, Jackson L, MacGurn J, Graham T.